Investigative and Regulatory Toxicolgist

Based around the vibrant Biotech and MedTech Startup community of Oxford, MedRow Scientific was launched in 2025 to help Medical Device and Life Sciences companies navigate their Research and Development challenges.

Cliff graduated with a first-class BSc (Hons) in Pharmacology from the University of Liverpool in 2000 before taking an MRC/SmithKline Beecham CASE PhD Studentship at the University of Aberdeen investigating the molecular mechanisms underlying the induction of drug metabolising Cytochrome P450 enzymes. Since completion of his PhD in 2004 Cliff has built a wealth of experience in R&D having worked for more than 20 years on diverse Toxicology, Life Sciences and Medical Device Development projects in academia and industry.

Specialities include:

• Medical Device Development (ISO 13485), Risk Assessment (ISO 14971) and Biocompatibility (ISO 10993), Sterilisation (ISO 11137 and ISO 11737), Endotoxin testing for Medical Devices, Manufacturing (GMP)

• Development and use of New Approach Methodologies (NAMs) for Toxicology testing

• Research models for Hepatotoxicity (in vitro testing)

• Bioanalytical method development for research use or clinical evaluations (GLP)

A publication list is provided for more information.

After postdoctoral projects at the Universities of Aberdeen, Liverpool and Manchester he moved to work in industry from 2013. As Principal Scientist at CN Bio Innovations he managed internal research activities developing Liver on Chip technology and worked across several internationally partnered projects.

In April 2015 Cliff joined OxSonics Therapeutics, working on a novel ultrasound mediated drug delivery technology designed to enhance the dose and distribution of biologics within solid tumours. As part of the Leadership Team (Development Director) he built and led the in-house biology and chemistry teams, managed internal proof of concept data generation, GMP manufacturing scale-up activities and GLP, ISO 10993 compliant preclinical safety assessments.

A committed life-long learner, Cliff maintains a strong scientific interest in Toxicology, Proteomics, Transcriptomics, Bioinformatics, New Approach Methodologies, Biosafety and Cell and Gene therapies. He is a member of the European Register of Toxicologists, and a current member of the Royal Society of Biology and The International Society for Cell & Gene Therapy.